Milling Equipment for API Pharmaceuticals

YOUR CHALLENGES

The Complexities of Making APIs

The API market will continue to expand as the incidences of chronic and lifestyle conditions increase due to an aging population, increasing demand for specialty drugs, increased focus on biopharmaceuticals and technological advancements.

Whilst this presents new opportunities for API manufacturers, development in this market comes with a range of challenges. Competitive price pressures emphasize the need for a process that provides high return on investment without compromising on quality.

Many of todays APIs require ever smaller particle sizes with tighter PSDs, which have a crucial impact on the properties of bio-availability and stability. The more potent molecules in development need to achieve the narrowest of Particle Size Distribution (PSDs).

In addition, some materials used in API manufacturing can be potentially hazardous, presenting concerns for operator safety and environmentally conscious material handling. This, in combination with the requirement to meet stringent quality and safety standards in the final product, means that process equipment must be safe for use and  provide ease of cleaning and maintenance without risk.

HOW WE CAN HELP

API Processing Equipment

Our size reduction equipment offers safer processing with OEL levels that meet the strictest industry standards required for API Processing. Along with producing consistent, repeatable results from batch to batch, without fail. Speed, accuracy and consistency are crucial to business success.

Quadro equipment has earned a reputation for quality, innovation and reliability. The mills are designed to safely handle pharmaceutical APIs and heat-sensitive products thanks to the low heat, low energy and low RPM operation of our conical mills that generates less dust than other types of mills. With no entrapment areas, the Quadro^® Comil^® offers straightforward maintenance, keeping production downtime to a minimum.

In our decades of experience working in the pharmaceutical industry, we have enabled clients to achieve smaller particle sizes & tighter particle size distributions than are possible using standard conical mills, hammer mills, or pin mills. This reduces waste for a better bottom line.

OUR EXPERIENCE

Decades in Pharma Milling

For almost 50 years, Quadro has been continually refining and improving our milling and sizing technology. During this time, we have partnered with our customers in a variety of drug therapy areas to achieve increased productivity, versatility and reliability.

Given the increasingly potent APIs that are being developed, we understand the significance of particle size in the manufacturing of APIs, and its related impact on bio-availability and shelf stability.

Our milling equipment is trusted across the globe for being able to successfully process Active Pharmaceutical Ingredients (APIs). We work with our customers to fully understand each particular application in order to find just the right solution to meet their requirements.

When you invest in Quadro^® Pharma Milling Equipment, you get more than just superior engineering and quality, you get access to our team of experts who will ensure you achieve your objectives.

OUR APPROACH

Milling and Sizing Solutions for API

No matter your application, our mills consistently deliver the batch-to-batch repeatability required to comply with the most demanding FDA standards. We adhere to ethical business principles and are committed to providing products of exceptional quality and value, backed by years of innovation and improvement.

Patented worldwide, our products are designed and manufactured to the highest standards of materials, finish and performance in sanitary equipment design. All of our cone mills are designed with consideration for operator safety, cleanability and process scale up, whilst maximizing efficiency.

Our pharmaceutical processing experts can help you solve your size-reduction challenges, whilst meeting the strictest quality control standards of the industry. Get in touch today to discover the ideal solution to your API processing challenges.